3.I.6B

Mathematical Biology
Part II, 2006

The SIR epidemic model for an infectious disease divides the population NN into three categories of susceptible S(t)S(t), infected I(t)I(t) and recovered (non-infectious) R(t)R(t). It is supposed that the disease is non-lethal, so that the population does not change in time.

Explain the reasons for the terms in the following model equations:

dSdt=pRrIS,dIdt=rISaI,dRdt=aIpR\frac{d S}{d t}=p R-r I S, \quad \frac{d I}{d t}=r I S-a I, \quad \frac{d R}{d t}=a I-p R

At time t=0,SNt=0, S \approx N while I,R1I, R \ll 1.

(a) Show that if rN<ar N<a no epidemic occurs.

(b) Now suppose that p>0p>0 and there is an epidemic. Show that the system has a nontrivial fixed point, and that it is stable to small disturbances. Show also that for both small and large pp both the trace and the determinant of the Jacobian matrix are O(p)O(p), and deduce that the matrix has complex eigenvalues for sufficiently small pp, and real eigenvalues for sufficiently large pp.