2.II.13B

Mathematical Biology
Part II, 2007

Show that the concentration C(x,t)C(\mathbf{x}, t) of a diffusible chemical substance in a stationary medium satisfies the partial differential equation

Ct=(DC)+F\frac{\partial C}{\partial t}=\nabla \cdot(D \nabla C)+F

where DD is the diffusivity and F(x,t)F(\mathbf{x}, t) is the rate of supply of the chemical.

A finite amount of the chemical, 4πM4 \pi M, is supplied at the origin at time t=0t=0, and spreads out in a spherically symmetric manner, so that C=C(r,t)C=C(r, t) for r>0,t>0r>0, t>0, where rr is the radial coordinate. The diffusivity is given by D=kCD=k C, for constant kk. Show, by dimensional analysis or otherwise, that it is appropriate to seek a similarity solution in which

C=Mα(kt)βf(ξ),ξ=r(Mkt)γ and 0ξ2f(ξ)dξ=1C=\frac{M^{\alpha}}{(k t)^{\beta}} f(\xi), \quad \xi=\frac{r}{(M k t)^{\gamma}} \quad \text { and } \quad \int_{0}^{\infty} \xi^{2} f(\xi) d \xi=1

where α,β,γ\alpha, \beta, \gamma are constants to be determined, and derive the ordinary differential equation satisfied by f(ξ)f(\xi).

Solve this ordinary differential equation, subject to appropriate boundary conditions, and deduce that the chemical occupies a finite spherical region of radius

r0(t)=(75Mkt)1/5r_{0}(t)=(75 M k t)^{1 / 5}

[Note: in spherical polar coordinates

C(Cr,0,0) and (V(r,t),0,0)1r2r(r2V)]\left.\nabla C \equiv\left(\frac{\partial C}{\partial r}, 0,0\right) \quad \text { and } \quad \nabla \cdot(V(r, t), 0,0) \equiv \frac{1}{r^{2}} \frac{\partial}{\partial r}\left(r^{2} V\right) \cdot\right]