Paper 2, Section II, A

Mathematical Biology
Part II, 2009

Consider the reaction system

Ak1X,B+Xk2Y,2X+Yk33X,Xk4E,A \stackrel{k_{1}}{\longrightarrow} X, \quad B+X \stackrel{k_{2}}{\longrightarrow} Y, \quad 2 X+Y \stackrel{k_{3}}{\longrightarrow} 3 X, \quad X \stackrel{k_{4}}{\longrightarrow} E,

where the kk s are the rate constants, and the reactant concentrations of AA and BB are kept constant. Write down the governing differential equation system for the concentrations of XX and YY and nondimensionalise the equations by setting u=αXu=\alpha X and v=αY,τ=k4tv=\alpha Y, \tau=k_{4} t so that they become

dudτ=1(b+1)u+au2v,dvdτ=buau2v\frac{d u}{d \tau}=1-(b+1) u+a u^{2} v, \quad \frac{d v}{d \tau}=b u-a u^{2} v

by suitable choice of α\alpha. Thus find aa and bb. Determine the positive steady state and show that there is a bifurcation value b=bc=1+ab=b_{c}=1+a at which the steady state becomes unstable to a Hopf bifurcation. Find the period of the oscillations in the neighbourhood of bcb_{c}.