Paper 3, Section I, A

Mathematical Biology
Part II, 2010

A population of aerobic bacteria swims in a laterally-infinite layer of fluid occupying <x<,<y<-\infty<x<\infty,-\infty<y<\infty, and d/2<z<d/2-d / 2<z<d / 2, with the top and bottom surfaces in contact with air. Assuming that there is no fluid motion and that all physical quantities depend only on zz, the oxygen concentration cc and bacterial concentration nn obey the coupled equations

ct=Dc2cz2knnt=Dn2nz2z(μncz)\begin{aligned} \frac{\partial c}{\partial t} &=D_{c} \frac{\partial^{2} c}{\partial z^{2}}-k n \\ \frac{\partial n}{\partial t} &=D_{n} \frac{\partial^{2} n}{\partial z^{2}}-\frac{\partial}{\partial z}\left(\mu n \frac{\partial c}{\partial z}\right) \end{aligned}

Consider first the case in which there is no chemotaxis, so nn has the spatially-uniform value nˉ\bar{n}. Find the steady-state oxygen concentration consistent with the boundary conditions c(±d/2)=c0c(\pm d / 2)=c_{0}. Calculate the Fick's law flux of oxygen into the layer and justify your answer on physical grounds.

Now allowing chemotaxis and cellular diffusion, show that the equilibrium oxygen concentration satisfies

d2cdz2kn0Dcexp(μc/Dn)=0\frac{d^{2} c}{d z^{2}}-\frac{k n_{0}}{D_{c}} \exp \left(\mu c / D_{n}\right)=0

where n0n_{0} is a suitable normalisation constant that need not be found.