Paper 3, Section I,
A model of wound healing in one spatial dimension is given by
where gives the density of healthy tissue at spatial position at time and and are positive constants.
By setting where , seek a steady travelling wave solution where tends to one for large negative and tends to zero for large positive . By linearising around the leading edge, where , find the possible wave speeds of the system. Assuming that the full nonlinear system will settle to the slowest possible speed, express the wave speed as a function of and .
Consider now a situation where the tissue is destroyed in some window of length , i.e. for for some constant and is equal to one elsewhere. Explain what will happen for subsequent times, illustrating your answer with sketches of . Determine approximately how long it will take for this wound to heal (in the sense that is close to one everywhere).